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4-hydroxy-3-Methoxyphenylglycol (piperazine salt)

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Catalog No. T37373Cas No. 67423-45-4

4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermediate. It is released into the blood and cerebrospinal fluid and has been used as a biochemical index of recent sympathetic nervous system activity.

4-hydroxy-3-Methoxyphenylglycol (piperazine salt)
Other Forms of 4-hydroxy-3-Methoxyphenylglycol (piperazine salt):

4-hydroxy-3-Methoxyphenylglycol (piperazine salt)

😃Good
Catalog No. T37373Cas No. 67423-45-4
4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermediate. It is released into the blood and cerebrospinal fluid and has been used as a biochemical index of recent sympathetic nervous system activity.
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10 mgInquiry35 days
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Product Introduction

Bioactivity
Description
4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermediate. It is released into the blood and cerebrospinal fluid and has been used as a biochemical index of recent sympathetic nervous system activity.
Chemical Properties
Molecular Weight454.52
FormulaC22H34N2O8
Cas No.67423-45-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS (pH 7.2): 1 mg/mL (2.2 mM), Sonication is recommended.
DMF: 25 mg/mL (55 mM), Sonication is recommended.
Ethanol: 10 mg/mL (22 mM), Sonication is recommended.
DMSO: 15 mg/mL (33 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM2.2001 mL11.0006 mL22.0012 mL110.0062 mL
Ethanol/DMSO/DMF
1mg5mg10mg50mg
5 mM0.4400 mL2.2001 mL4.4002 mL22.0012 mL
10 mM0.2200 mL1.1001 mL2.2001 mL11.0006 mL
20 mM0.1100 mL0.5500 mL1.1001 mL5.5003 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Keywords

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