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7-O-(Amino-PEG4)-paclitaxel is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system in cells.
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500 mg | Inquiry | Backorder |
Description | 7-O-(Amino-PEG4)-paclitaxel is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system in cells. |
In vitro | PROTACs comprise two distinct ligands linked together: one that binds to an E3 ubiquitin ligase and another that targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 1101.19 |
Formula | C58H72N2O19 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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