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Fmoc-Val-Cit-PAB-MMAE

🥰Excellent
Catalog No. T17983Cas No. 1350456-56-2

Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.

Fmoc-Val-Cit-PAB-MMAE

Fmoc-Val-Cit-PAB-MMAE

🥰Excellent
Purity: 98.2%
Catalog No. T17983Cas No. 1350456-56-2
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.
Pack SizePriceAvailabilityQuantity
1 mg$37In Stock
5 mg$91In Stock
10 mg$148In Stock
25 mg$267In Stock
50 mg$395In Stock
100 mg$562In Stock
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Purity:98.2%
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Product Introduction

Bioactivity
Description
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.
Chemical Properties
Molecular Weight1345.67
FormulaC73H104N10O14
Cas No.1350456-56-2
Smiles[H][C@]([C@@H](C)CC)([C@@H](CC(=O)N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(C)C)cc1)C(C)C
Relative Density.1.198 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (22.29 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.7431 mL3.7156 mL7.4312 mL37.1562 mL
5 mM0.1486 mL0.7431 mL1.4862 mL7.4312 mL
10 mM0.0743 mL0.3716 mL0.7431 mL3.7156 mL
20 mM0.0372 mL0.1858 mL0.3716 mL1.8578 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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