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Azido-PEG5-alcohol, a non-cleavable 5 unit polyethylene glycol (PEG) ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG5-alcohol, a non-cleavable 5 unit polyethylene glycol (PEG) ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2]. |
In vitro | ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker[1]. PROTACs contain two ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 263.29 |
Formula | C10H21N3O5 |
Cas No. | 86770-68-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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