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Biotin-PEG6-Thalidomide

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Catalog No. T17592Cas No. 2144775-48-2

Biotin-PEG6-Thalidomide is a PROTAC linker based on PEG.

Biotin-PEG6-Thalidomide

Biotin-PEG6-Thalidomide

😃Good
Catalog No. T17592Cas No. 2144775-48-2
Biotin-PEG6-Thalidomide is a PROTAC linker based on PEG.
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Product Introduction

Bioactivity
Description
Biotin-PEG6-Thalidomide is a PROTAC linker based on PEG.
Chemical Properties
Molecular Weight791.91
FormulaC37H53N5O12S
Cas No.2144775-48-2
SmilesO=C1N(C(=O)C=2C1=CC=CC2)C3C(=O)N(CCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)C(=O)CC3
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (113.7 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2628 mL6.3138 mL12.6277 mL63.1385 mL
5 mM0.2526 mL1.2628 mL2.5255 mL12.6277 mL
10 mM0.1263 mL0.6314 mL1.2628 mL6.3138 mL
20 mM0.0631 mL0.3157 mL0.6314 mL3.1569 mL
50 mM0.0253 mL0.1263 mL0.2526 mL1.2628 mL
100 mM0.0126 mL0.0631 mL0.1263 mL0.6314 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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