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CJC-1295 acetate(863288-34-0 free base)

Catalog No. TP2328L CAS TP2328L

Synonyms: DAC:GRF acetate

CJC-1295 acetate(863288-34-0 free base) (DAC:GRF acetate) is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS)

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CJC-1295 acetate(863288-34-0 free base) Chemical Structure

CJC-1295 acetate(863288-34-0 free base), CAS TP2328L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
5 mg	In stock	$ 302.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 747.00
50 mg	In stock	$ 1,050.00
100 mg	In stock	$ 1,420.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

In vivo

CJC-1295 markedly increases plasma growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels in both animals and humans.[1] With a single injection, in human subjects, CJC-1295 increases plasma GH levels by 2- to 10-fold for 6 days or longer and plasma IGF-1 levels by 0.5- to 3-fold for 9 to 11 days.[3] The drug has an estimated half-life of about 6 to 8 days in humans.[3] With multiple doses of CJC-1295, IGF-1 levels were found to remain elevated in humans for up to 28 days

Synonyms	DAC:GRF acetate
Molecular Weight	3428.01
Formula	C154H256N44O44
CAS No.	TP2328L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

References and Literature

1. Jetté L, Léger R, Thibaudeau K, Benquet C, Robitaille M, Pellerin I, et al. (July 2005). "Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog". Endocrinology. 146 (7): 3052–8. 2. Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R (December 2006). "Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse". American Journal of Physiology. Endocrinology and Metabolism. 291 (6): E1290-4 3. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA (March 2006). "Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults". The Journal of Clinical Endocrinology and Metabolism. 91 (3): 799–805.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library GPCR Compound Library NO PAINS Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CJC-1295 acetate(863288-34-0 free base) TP2328L GPCR/G Protein GHSR DAC:GRF acetate CJC1295 acetate(863288340 free base) CJC 1295 acetate(863288 34 0 free base) DAC:GRF Acetate inhibitor inhibit

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