Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin. is a cell wall biosynthesis inhibitor with a broad spectrum of activity against Gram-positive and Gram-negative bacteria.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 30.00 | |
5 mg | 5 days | $ 44.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 54.00 |
Description | Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin. is a cell wall biosynthesis inhibitor with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. |
In vitro | Cefozopran hydrochloride (SCE-2787 hydrochloride), a fourth-generation cephalosporin, exhibits substantial activity against a range of bacteria. Cefozopran hydrochloride is effective against gram-positive organisms, including methicillin-susceptible staphylococci, enterococci, and viridans group streptococci. Additionally, Cefozopran hydrochloride demonstrates efficacy against gram-negative organisms such as Hemophilus influenza. Notably, Cefozopran hydrochloride displays comparatively good activity against enterococci and P. aeruginosa, which are typically resistant to other cephalosporins[2]. |
In vivo | In four-week-old ICR male mice, Cefozopran hydrochloride, administered subcutaneously at doses ranging from 5 to 80 mg/kg twice a day for 5 days, proves effective against acute respiratory tract infections caused by Kiebsiella pneumonia DT-S. In a model of chronic respiratory tract infection induced by K. pneumoniae 27, Cefozopran hydrochloride, at doses between 20 and 80 mg/kg administered subcutaneously twice a day for 7 days in five-week-old CBA/J female mice, exhibits effectiveness comparable to Ceftazidime[2]. |
Synonyms | SCE-2787 hydrochloride |
Molecular Weight | 551.99 |
Formula | C19H18ClN9O5S2 |
CAS No. | 113981-44-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 30 mg/mL (54.35 mM), sonification is recommended.
DMSO: 30 mg/mL (54.35 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cefozopran hydrochloride 113981-44-5 Microbiology/Virology Antifungal Cefozopran Hydrochloride SCE2787 Hydrochloride SCE-2787 Hydrochloride SCE-2787 hydrochloride SCE 2787 Hydrochloride inhibitor inhibit