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Chlorobutanol hemihydrate

🥰Excellent
Catalog No. T67058Cas No. 6001-64-5
Alias Chlorbutol hemihydrate

Chlorobutanol hemihydrate (Chlorbutol hemihydrate) is an orally toxic preservative with antimicrobial activity that inhibits Gram-positive and Gram-negative bacteria and fungi, inhibits the aggregation and release of human platelets in vitro, and is commonly used in cosmetics.

Chlorobutanol hemihydrate

Chlorobutanol hemihydrate

🥰Excellent
Catalog No. T67058Alias Chlorbutol hemihydrateCas No. 6001-64-5
Chlorobutanol hemihydrate (Chlorbutol hemihydrate) is an orally toxic preservative with antimicrobial activity that inhibits Gram-positive and Gram-negative bacteria and fungi, inhibits the aggregation and release of human platelets in vitro, and is commonly used in cosmetics.
Pack SizePriceAvailabilityQuantity
1 g$31In Stock
5 g$70In Stock
10 g$98In Stock
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Product Introduction

Bioactivity
Description
Chlorobutanol hemihydrate (Chlorbutol hemihydrate) is an orally toxic preservative with antimicrobial activity that inhibits Gram-positive and Gram-negative bacteria and fungi, inhibits the aggregation and release of human platelets in vitro, and is commonly used in cosmetics.
In vivo
The high dose was set at 100 mg/kg/day and the medium, medium-low, and low doses were set at 50 mg/kg/day, 25 mg/kg/day, and 12.5 mg/kg/day, respectively, in a 28-day repeated-dose toxicity study by gavage.There was no significant change in body weight in the repeated-dose toxicity study.100 mg/kg/day The relative weights of liver and kidney were significantly increased in both sexes in the dose group.[1]
AliasChlorbutol hemihydrate
Chemical Properties
Molecular Weight186.46
FormulaC4H7Cl3O 1/2H2O
Cas No.6001-64-5
SmilesClC(Cl)(Cl)C(O)(C)C.O 0.5H2O
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL(429.05 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.3631 mL26.8154 mL53.6308 mL268.1540 mL
5 mM1.0726 mL5.3631 mL10.7262 mL53.6308 mL
10 mM0.5363 mL2.6815 mL5.3631 mL26.8154 mL
20 mM0.2682 mL1.3408 mL2.6815 mL13.4077 mL
50 mM0.1073 mL0.5363 mL1.0726 mL5.3631 mL
100 mM0.0536 mL0.2682 mL0.5363 mL2.6815 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
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μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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