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DOTAP chloride

DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a useful and effective cationic lipid transfection DNA(plasmids, BacMIDs) and modified nucleic acids (antisense oligonucleotides) without the use of auxiliary lipids.

Catalog No. T11086Cas No. 132172-61-3

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Purity:100%

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COA HNMR HPLC

DOTAP chloride

Catalog No. T11086Cas No. 132172-61-3

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
25 mg	$31	In Stock
50 mg	$44	In Stock
100 mg	$81	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Product Introduction

Bioactivity

Description	DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a useful and effective cationic lipid transfection DNA(plasmids, BacMIDs) and modified nucleic acids (antisense oligonucleotides) without the use of auxiliary lipids.
Targets&IC50	Cationic Lipid:
Alias	1,2-Dioleoyl-3-trimethylammonium-propane chloride

Chemical Properties

Molecular Weight	698.54
Formula	C₄₂H₈₀ClNO₄
Cas No.	132172-61-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 125 mg/mL (178.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4316 mL	7.1578 mL	14.3156 mL	71.5779 mL
5 mM	0.2863 mL	1.4316 mL	2.8631 mL	14.3156 mL
10 mM	0.1432 mL	0.7158 mL	1.4316 mL	7.1578 mL
20 mM	0.0716 mL	0.3579 mL	0.7158 mL	3.5789 mL
50 mM	0.0286 mL	0.1432 mL	0.2863 mL	1.4316 mL
100 mM	0.0143 mL	0.0716 mL	0.1432 mL	0.7158 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DOTAP chloridenucleicacidInhibitortransfectionLipid1,2-Dioleoyl-3-trimethylammonium-propane ChlorideDOTAPDOTAP ChlorideinhibitCationic