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G3-C12
Catalog No. T11346Cas No. 848301-94-0
G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
G3-C12
Catalog No. T11346Cas No. 848301-94-0
G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
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| 500 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM. |
| Targets&IC50 | GAL3:(kd)88 nM |
| In vitro | G3-C12, an opolymer incorporating N-(2-hydroxypropyl)methacrylamide (HPMA), demonstrates potent and selective affinity for colorectal cancer (CRC) cells overexpressing galectin-3, exhibiting enhanced targeting capabilities compared to its galactose-based counterparts. As a galectin-3 binding peptide, G3-C12 has a high affinity (Kd) of 88 nM but lacks affinity for other members of the galectin family or unrelated lectins. |
| Molecular Weight | 1758.99 |
| Formula | C74H115N23O23S2 |
| Cas No. | 848301-94-0 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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