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GJ103

Catalog No. T3448Cas No. 1459687-89-8

GJ103 sodium salt is an active analog of the read-through compound GJ072. Some GJ072 analogs (e.g., GJ103, GJ106, GJ109, and GJ111) consistently demonstrates their activities in all three PTCs by both FCATMpSer1981 and IRIF assays. GJ103 have similar read-through activity as RTC13 or RTC14, but are more tolerable than RTC13 and RTC14 to A-T cells.

GJ103

GJ103

Purity: 99.1%
Catalog No. T3448Cas No. 1459687-89-8
GJ103 sodium salt is an active analog of the read-through compound GJ072. Some GJ072 analogs (e.g., GJ103, GJ106, GJ109, and GJ111) consistently demonstrates their activities in all three PTCs by both FCATMpSer1981 and IRIF assays. GJ103 have similar read-through activity as RTC13 or RTC14, but are more tolerable than RTC13 and RTC14 to A-T cells.
Pack SizePriceAvailabilityQuantity
2 mg$29In Stock
5 mg$47In Stock
10 mg$79In Stock
25 mg$157In Stock
50 mg$190In Stock
100 mg$232In Stock
200 mg$283In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.1%
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Product Introduction

Bioactivity
Description
GJ103 sodium salt is an active analog of the read-through compound GJ072. Some GJ072 analogs (e.g., GJ103, GJ106, GJ109, and GJ111) consistently demonstrates their activities in all three PTCs by both FCATMpSer1981 and IRIF assays. GJ103 have similar read
Chemical Properties
Molecular Weight342.37
FormulaC16H14N4O3S
Cas No.1459687-89-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 65 mg/mL (189.85 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9208 mL14.6041 mL29.2082 mL146.0408 mL
5 mM0.5842 mL2.9208 mL5.8416 mL29.2082 mL
10 mM0.2921 mL1.4604 mL2.9208 mL14.6041 mL
20 mM0.1460 mL0.7302 mL1.4604 mL7.3020 mL
50 mM0.0584 mL0.2921 mL0.5842 mL2.9208 mL
100 mM0.0292 mL0.1460 mL0.2921 mL1.4604 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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