Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan). GSK8814 displays 500-fold selectivity for ATAD2 over BRD4 BD1. GSK8814 binds to ATAD2 and BRD4 BD1 (pIC50s: 7.3 and 4.6).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,280.00 | |
50 mg | 10-14 weeks | $ 1,670.00 | |
100 mg | 10-14 weeks | $ 2,530.00 |
Description | GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan). GSK8814 displays 500-fold selectivity for ATAD2 over BRD4 BD1. GSK8814 binds to ATAD2 and BRD4 BD1 (pIC50s: 7.3 and 4.6). |
Targets&IC50 | ATAD2:8 nM (ki), ATAD2:8.9 (pki), BRD4 BD1:4.6 (pic50) |
Molecular Weight | 527.61 |
Formula | C28H35F2N5O3 |
CAS No. | 1997369-78-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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GSK8814 1997369-78-4 Chromatin/Epigenetic Epigenetic Reader Domain GSK-8814 GSK 8814 inhibitor inhibit