Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 35 days | $ 1,440.00 |
Description | JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC. |
Targets&IC50 | Cereblon:, CDK8:159 nM |
Molecular Weight | 920.161 |
Formula | C53H69N5O9 |
CAS No. | 2209085-22-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JH-XI-10-02 2209085-22-1 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR JHXI1002 JH XI 10 02 inhibitor inhibit