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MitoBloCK-11 (MB-11)

Catalog No. T8782Cas No. 413606-16-3

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.

MitoBloCK-11 (MB-11)

MitoBloCK-11 (MB-11)

Purity: 98.03%
Catalog No. T8782Cas No. 413606-16-3
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
Pack SizePriceAvailabilityQuantity
1 mg$64In Stock
5 mg$148In Stock
10 mg$227In Stock
25 mg$376In Stock
50 mg$530In Stock
100 mg$713In Stock
200 mg$962In Stock
1 mL x 10 mM (in DMSO)$171In Stock
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Purity:98.03%
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Product Introduction

Bioactivity
Description
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
Chemical Properties
Molecular Weight434.26
FormulaC17H12BrN3O4S
Cas No.413606-16-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (57.57 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3028 mL11.5138 mL23.0277 mL115.1384 mL
5 mM0.4606 mL2.3028 mL4.6055 mL23.0277 mL
10 mM0.2303 mL1.1514 mL2.3028 mL11.5138 mL
20 mM0.1151 mL0.5757 mL1.1514 mL5.7569 mL
50 mM0.0461 mL0.2303 mL0.4606 mL2.3028 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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