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PD-1-IN-17

Catalog No. T12377Cas No. 1673560-66-1

PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.

PD-1-IN-17

PD-1-IN-17

Catalog No. T12377Cas No. 1673560-66-1
PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.
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1 mg$11035 days
5 mg$49535 days
10 mg$87835 days
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Product Introduction

Bioactivity
Description
PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.
Chemical Properties
Molecular Weight374.35
FormulaC13H22N6O7
Cas No.1673560-66-1
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 112.5 mg/mL (300.5 mM), Sonication is recommended.
H2O: 90.0 mg/mL (240.4 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.6713 mL13.3565 mL26.7130 mL133.5648 mL
5 mM0.5343 mL2.6713 mL5.3426 mL26.7130 mL
10 mM0.2671 mL1.3356 mL2.6713 mL13.3565 mL
20 mM0.1336 mL0.6678 mL1.3356 mL6.6782 mL
50 mM0.0534 mL0.2671 mL0.5343 mL2.6713 mL
100 mM0.0267 mL0.1336 mL0.2671 mL1.3356 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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