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Pseudohypericin

Catalog No. TN2115 CAS 55954-61-5

Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS.

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Pseudohypericin, CAS 55954-61-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS.

In vitro

Since hypericin has been proposed as a photosensitizer for photodynamic cancer therapy, the photocytotoxicity of its congener Pseudohypericin has been investigated. The presence of foetal calf serum (FCS) or albumin extensively inhibits the photocytotoxic effect of Pseudohypericin against A431 tumour cells, and is associated with a large decrease in cellular uptake of the compound. These results suggest that Pseudohypericin, in contrast to hypericin, interacts strongly with constituents of FCS, lowering its interaction with cells[1]

Molecular Weight	520.44
Formula	C30H16O9
CAS No.	55954-61-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Photocytotoxic effect of pseudohypericin versus hypericin.J.Photoch.Photobiol. B , 1998, 45(2-3):87-94.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Pseudohypericin 55954-61-5 GPCR/G Protein Immunology/Inflammation Others Prostaglandin Receptor Inhibitor inhibitor inhibit

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