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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $36 | In Stock | |
5 mg | $87 | In Stock | |
10 mg | $157 | In Stock | |
25 mg | $357 | In Stock | |
50 mg | $533 | In Stock | |
100 mg | $769 | In Stock | |
1 mL x 10 mM (in DMSO) | $96 | In Stock |
Description | SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM). |
In vitro | SR144528(1 μM) stimulates the forskolin-sensitive adenylyl cyclase activity in CHO-CB2 cells in a concentration-dependent manner with an EC50 of 26 nM[1]. In Raw 264.7 macrophages, SR144528 reduces the activity of caspase 3. SR144528(10 μM) inhibits microsomal ACAT activity(68%)[2]. |
In vivo | SR144528 enhances delayedgastric emptying[3]. |
Molecular Weight | 476.05 |
Formula | C29H34ClN3O |
Cas No. | 192703-06-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45.0 mg/mL (94.5 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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