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Sulfaclozine sodium

Catalog No. T16953 CAS 23307-72-4

Synonyms: Sulfachloropyrazine sodium

Sulfaclozine sodium is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases.

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Sulfaclozine sodium, CAS 23307-72-4

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Sulfaclozine sodium is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases.
In vitro	Sulfaclozine is weakly adsorbed on the surface of TiO2 at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8 in ultra pure water [2].
In vivo	Sulfaclozine (60 mg/kg; intravenous injection or p.o.; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract [1].

Synonyms	Sulfachloropyrazine sodium
Molecular Weight	307.71
Formula	C10H9ClN4NaO2S
CAS No.	23307-72-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 50 mg/mL (163.03 mM), Sonication is recommended.

References and Literature

1. Sentepe I, et al. Pharmacokinetic of sulfaclozine in broiler chickens. Food Chem Toxicol. 2010 Jan;48(1):448-451. 2. Ismail L, et al. Effect of water constituents on the degradation of sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Environ Sci Pollut Res Int. 2018 Jan;25(3):2651-2663.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sulfaclozine sodium 23307-72-4 Microbiology/Virology Antibacterial Sulfachloropyrazine sodium inhibitor inhibit

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