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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $48 | In Stock |
Description | Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity. |
In vivo | Tranylcypromine-induced transcriptional and epigenetic regulation modulated RGC survival via the promotion of p38 MAPKγ activity. Therefore, pharmacologic treatments that suppress LSD1 activity may be a novel therapeutic strategy that can be used to treat neurodegenerative diseases[1]. |
Animal Research | The authors evaluated whether tranylcypromine contributes to neuronal survival following stress-induced damage using primary cultured rat RGCs and in vivo N-methyl-D-aspartate (NMDA)-induced excitotoxicity.?Additionally, the molecules associated with tranylcypromine treatment were assessed by microarray and immunoblot analysis[1]. |
Alias | Tranylcypromine Sulfate, Tranylcypromine (hemisulfate) |
Molecular Weight | 182.23 |
Formula | C9H11N 1/2H2SO4 |
Cas No. | 13492-01-8 |
Storage | store at low temperature | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 10 mg/mL (54.8 mM), Sonication is recommended. ![]() DMSO: 3.33 mg/mL (18 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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