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Amino-PEG36-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Amino-PEG36-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one targets an E3 ubiquitin ligase, and the other targets a specific protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 1717.07 |
Formula | C78H157NO38 |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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