aminopeg36ch2boc

Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate can be used as a building block for the synthesis of various biologically active molecules such as peptides, proteins, and nucleic acids.

RS09 2TFA (1449566-36-2 free base) is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. It acts as an adjuvant in vivo and enhances X-15 specific antibody serum concentrations.

Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc can also be used in the synthesis of PROTAC.

(2-Pyridyldithio)-PEG2-Boc is a polyethylene glycol-based PROTAC linker utilized for the synthesis of PROTACs[1].

Boc-2-Pal-OH is an amino acid derivative and has a wide range of applications in life science related research.

Neuropeptide Y (2-36) (porcine) is a pig-sourced peptide closely resembling its rat and human counterparts with 97.14% homology. It acts as an agonist for rat neuropeptide receptors Y5, Y2, and Y1, demonstrating EC50 values of 1.2, 1.6, and 3.4 nM, respectively. This compound is utilized in research on obesity and eating disorders [1].

Boc-Arg(Z)2-OH is an amino acid derivative and has a wide range of applications in life science related research.

Boc-(R)-2-thienylglycine is a useful organic compound for research related to life sciences. The catalog number is T65017 and the CAS number is 74562-03-1.

Boc-Phe(2-Me)-OH is an amino acid derivative and has a wide range of applications in life science related research.

VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated anticancer efficacy. It modulates apoptotic pathways by upregulating BAX and downregulating Bcl-2, leading to cytotoxic effects on cancer cell lines, including MCF-7 (IC50 = 0.42 μM) and HepG2 (IC50 = 0.22 μM) [1].

SARS-CoV-2-IN-36 is a potent inhibitor of SARS-CoV-2 Mpro (SARS-CoV), demonstrating an IC50 of 2.37 μM and a Kd of 1.19 μM in enzymatic assays. This compound exhibits antiviral activity against SARS-CoV-2 variants UC-1074, RG2674, and NVDBB-2220 in Vero cells.

Boc-D-2-Pal-OH is an amino acid derivative and has a wide range of applications in life science related research.

Boc-D-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66189 and the CAS number is 76985-10-9.

Boc-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66060 and the CAS number is 58438-04-3.

Boc-Lys(2-Cl-Z)-OH is a useful organic compound for research related to life sciences. The catalog number is T67521 and the CAS number is 54613-99-9.

Boc-D-Tyr(2-Br-Z)-OH is a useful organic compound for research related to life sciences. The catalog number is T66218 and the CAS number is 81189-61-9.

Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].

Boc-Tyr(2-Br-Z)-OH is a useful organic compound for research related to life sciences. The catalog number is T67623 and the CAS number is 47689-67-8.

Boc-D-Phe(2-Me)-OH is an amino acid derivative and has a wide range of applications in life science related research.

Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker employed in the synthesis of PROTACs[1].

Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Boc-D-Lys(2-Cl-Z)-OH is a useful organic compound for research related to life sciences. The catalog number is T66057 and the CAS number is 57096-11-4.

Amino-PEG36-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.