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Amino-PEG9-Boc is a PEG-based linker for PROTACs, essential for joining two ligands in PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $36 | 5 days | |
5 mg | $55 | 5 days |
Description | Amino-PEG9-Boc is a PEG-based linker for PROTACs, essential for joining two ligands in PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 541.67 |
Formula | C25H51NO11 |
Cas No. | 1818294-44-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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