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Anthraflavic acid

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Purity:98%

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COA HNMR

Anthraflavic acid

Catalog No. T5941Cas No. 84-60-6

Anthraflavic acid (2,6-Dihydroxyanthraquinone), a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor.

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Pack Size	Price	Availability	Quantity
100 mg	$41	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Product Introduction

Bioactivity

Description	Anthraflavic acid (2,6-Dihydroxyanthraquinone), a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor.
In vitro	Anthraflavic acid is a potent inhibitor of IQ mutagenicity by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways.
Kinase Assay	The metabolic activation of IQ to mutagens was determined using the Ames mutagenicity test ?and employing Salmonella lyphimurium strain TA98 ?and 10% hepatic preparations as activation systems.?IQ and anthraflavic acid were dissolved in DMSO so that the solvent levels never exceeded 100 μl?per phile.?In experiments where microsomes onl~ were used as the activation system, $9 mix was supplemented with 1 unit/plate of glucose-6-phosphate dehydrogenase.?Pre-incubation conditions are described in the appropriate legends.
Alias	2,6-Dihydroxyanthraquinone

Chemical Properties

Molecular Weight	240.21
Formula	C14H8O4
Cas No.	84-60-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5.5 mg/mL (22.9 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1630 mL	20.8151 mL	41.6302 mL	208.1512 mL
5 mM	0.8326 mL	4.1630 mL	8.3260 mL	41.6302 mL
10 mM	0.4163 mL	2.0815 mL	4.1630 mL	20.8151 mL
20 mM	0.2082 mL	1.0408 mL	2.0815 mL	10.4076 mL

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In Vivo Formulation Calculator (Clear solution)

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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