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ART-CHEM-BB B025267

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Catalog No. T9821Cas No. 381208-40-8

ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.

ART-CHEM-BB B025267

ART-CHEM-BB B025267

🥰Excellent
Purity: 98.14%
Catalog No. T9821Cas No. 381208-40-8
ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
5 mg$262In Stock
10 mg$388In Stock
25 mg$592In Stock
50 mg$828In Stock
100 mg$1,110In Stock
200 mg$1,480In Stock
1 mL x 10 mM (in DMSO)$250In Stock
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Purity:98.14%
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Product Introduction

Bioactivity
Description
ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.
Targets&IC50
Utrophin:1.8 μM (EC50)
Chemical Properties
Molecular Weight295.38
FormulaC17H21N5
Cas No.381208-40-8
SmilesCCN(CC)C1=CC=C(C=C1)N1N=C2C=C(C)C(N)=CC2=N1
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (186.2 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3855 mL16.9273 mL33.8547 mL169.2735 mL
5 mM0.6771 mL3.3855 mL6.7709 mL33.8547 mL
10 mM0.3385 mL1.6927 mL3.3855 mL16.9273 mL
20 mM0.1693 mL0.8464 mL1.6927 mL8.4637 mL
50 mM0.0677 mL0.3385 mL0.6771 mL3.3855 mL
100 mM0.0339 mL0.1693 mL0.3385 mL1.6927 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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