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Azido-PEG10-NHS ester is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules, and enables selective protein degradation by leveraging the [ubiquitin-proteasome system] within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG10-NHS ester is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules, and enables selective protein degradation by leveraging the [ubiquitin-proteasome system] within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. Utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1]. |
Molecular Weight | 652.69 |
Formula | C27H48N4O14 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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