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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $308 | In Stock |
Description | Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation and can be used to ameliorate cognitive impairments and memory disorders. |
In vitro | The anti-proliferative effect of BAY 60-7550 (1 μM) is pronounced, with a significant decrease in proliferation observed in PASMCs from IPAH patients compared to untreated control cells[2]. |
In vivo | Administration of the PDE2 inhibitors Bay 60-7550 (0.5, 1, and 3 mg/kg) or ND7001 (1 mg/kg), or the NO donor detanonoate (0.5 mg/kg), antagonized the anxiety-like behavior induced by restraint stress in mice [1]. |
Alias | BAY 607550 |
Molecular Weight | 476.57 |
Formula | C27H32N4O4 |
Cas No. | 439083-90-6 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (62.89 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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