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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $328 | In Stock | |
5 mg | $783 | In Stock | |
10 mg | $1,080 | In Stock | |
25 mg | $1,570 | In Stock | |
50 mg | $1,970 | In Stock | |
100 mg | $2,480 | In Stock | |
500 mg | $4,910 | In Stock |
Description | BB-78485 is a potent small molecule inhibitor of LpxC metalloenzymes with antibacterial activity. The IC50 value of BB-78485 against LpxC is 160 nM. BB-78485 can be used for the study of Gram-negative bacterial infections. |
In vitro | BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].BB-78485 is effective against D21 and D22 (lpxC101), with MIC values of 2 μg/mL and 0.016 μg/mL, respectively[1].The MIC values of BB-78485 against Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia range from 1 μg/mL to 32 μg/mL[1]. |
Alias | BB78485, BB 78485 |
Molecular Weight | 420.48 |
Formula | C23H20N2O4S |
Cas No. | 207732-11-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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