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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Biotin-bis-amido-SS-NHS is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. |
In vitro | Biotin-bis-amido-SS-NHS, characterized by its long-arm structure and a disulfide bond, is utilized in the biochemistry detection field to minimize steric hindrance effects, thereby enhancing detection sensitivity[1]. PROTACs, constructed with two distinct ligands linked by a connector, exploit one ligand for E3 ubiquitin ligase and another for the target protein, leveraging the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. |
Molecular Weight | 575.72 |
Formula | C22H33N5O7S3 |
Cas No. | 142439-92-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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