Shopping Cart
- Remove All
Your shopping cart is currently empty
Bis-PEG2-PFP ester
😃Good
Catalog No. T14633Cas No. 1314378-18-1
Bis-PEG2-PFP ester is a non-cleavable 2-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, Bis-PEG2-PFP ester serves as a PEG-based linker for the synthesis of proteolysis targeting chimeras (PROTACs) [2].
Bis-PEG2-PFP ester
😃Good
Catalog No. T14633Cas No. 1314378-18-1
Bis-PEG2-PFP ester is a non-cleavable 2-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, Bis-PEG2-PFP ester serves as a PEG-based linker for the synthesis of proteolysis targeting chimeras (PROTACs) [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | Inquiry | Backorder | |
| 500 mg | Inquiry | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Bis-PEG2-PFP ester"
Succinic anhydride
T18723108-30-5
Succinic anhydride is a cyclic anhydride. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide.
- $29
Size
QTY
EMCS
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
T1406155750-63-5
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.
- $46
Size
QTY
Fmoc-8-amino-3,6-dioxaoctanoic acid
Fmoc-NH-PEG2-CH2COOH
T15304166108-71-0
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.
- $29
Size
QTY
DSG Crosslinker
T1517179642-50-5
DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
- $39
Size
QTY
Fmoc-Gly-Gly-OH
T1795235665-38-4
Fmoc-Gly-Gly-OH, a cleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).
- $30
Size
QTY
DSS Crosslinker
T1517668528-80-3
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is a homobifunctional crosslinker that is cell membrane permeable, with amine-reactive NHS esters at both ends of an 8-atom [11.4 angstrom] spacer arm for conjugating proteins, including intracellular proteins.
- $41
Size
QTY
SMCC
N-Succinimidyl 4-(N-maleimidomethyl)cycl
T911664987-85-5
SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker.
- $30
Size
QTY
Boc-NH-PEG4-CH2COOH
T14746876345-13-0
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].
- $29
Size
QTY
DSP Crosslinker
Cited
T1517557757-57-0
DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].
- $30
Size
QTY
CitedVal-cit-PAB-OH
T17213159857-79-1
Val-cit-PAB-OH is an ADC linker that is cleavable.
- $29
Size
QTY
FMoc-Val-Cit-PAB-PNP
T7767863971-53-3
Fmoc-Val-Cit-PAB-PNP is a linker used in Antibody-Drug Conjugation (ADC).
- $116
Size
QTY
N-Boc-PEG5-bromide
T162181392499-32-9
N-Boc-PEG5-bromide is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and serves as a PROTAC linker based on PEG and Alkyl/ether.
- $29
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Bis-PEG2-PFP ester is a non-cleavable 2-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, Bis-PEG2-PFP ester serves as a PEG-based linker for the synthesis of proteolysis targeting chimeras (PROTACs) [2]. |
| In vitro | ADCs consist of an antibody linked to a cytotoxin through an ADC linker[1]. PROTACs feature two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| Molecular Weight | 538.29 |
| Formula | C20H12F10O6 |
| Cas No. | 1314378-18-1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Bis-PEG2-PFP ester | purchase Bis-PEG2-PFP ester | Bis-PEG2-PFP ester cost | order Bis-PEG2-PFP ester | Bis-PEG2-PFP ester chemical structure | Bis-PEG2-PFP ester in vitro | Bis-PEG2-PFP ester formula | Bis-PEG2-PFP ester molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.