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BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune responses in a dose-dependent manner and can be used to study immune-related diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $126 | In Stock | |
5 mg | $313 | In Stock | |
10 mg | $488 | In Stock | |
25 mg | $819 | In Stock | |
50 mg | $1,080 | In Stock | |
100 mg | $1,490 | In Stock |
Description | BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune responses in a dose-dependent manner and can be used to study immune-related diseases. |
Targets&IC50 | DGK ζ:2.1nM, DGK α:4.6 nM |
Molecular Weight | 516.5 |
Formula | C27H22F2N6O3 |
Cas No. | 2407854-18-4 |
Smiles | N#CC1=NC2=C(N(C)C(C([N+]([O-])=O)=C2N3CCN(C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3)=O)C=C1 |
Relative Density. | no data available |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (154.89 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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