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Boc-NH-PEG5-CH2CH2COOH is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Boc-NH-PEG5-CH2CH2COOH is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one targets an E3 ubiquitin ligase and the other targets the [protein]. They harness the intracellular ubiquitin-proteasome system to selectively degrade these [proteins]. |
Molecular Weight | 409.47 |
Formula | C18H35NO9 |
Cas No. | 1347750-78-0 |
Relative Density. | 1.123 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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