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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 1-2 weeks | |
50 mg | $1,980 | 1-2 weeks | |
100 mg | $2,500 | 1-2 weeks |
Description | BPK-29, a ligand specifically targeting the atypical orphan nuclear receptor NR0B1, disrupts its protein interactions through covalent modification at C274, thereby impairing the anchorage-independent growth of KEAP1-mutant cancer cells. |
In vitro | BPK-29 effectively targets NR0B1, demonstrating considerable proteomic selectivity within KEAP1-mutant Non-Small Cell Lung Cancers (NSCLCs)[1]. |
Molecular Weight | 470 |
Formula | C26H32ClN3O3 |
Cas No. | 2143467-62-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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