Shopping Cart

Remove All

Your shopping cart is currently empty

BPK-29 hydrochloride

Select Batch

Purity:99.19%

Resource Download

COA HNMR HPLC

BPK-29 hydrochloride

Catalog No. T13586LCas No. 2444815-73-8

BPK-29 hydrochloride is a specific ligand that disrupts atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274, impairing the anchorage-independent growth of [KEAP1-mutant cancer cells].

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$31	In Stock
2 mg	$43	In Stock
5 mg	$71	In Stock
10 mg	$128	In Stock
25 mg	$258	In Stock
50 mg	$478	In Stock
100 mg	$689	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "BPK-29 hydrochloride"

Product Introduction

Bioactivity

Description	BPK-29 hydrochloride is a specific ligand that disrupts atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274, impairing the anchorage-independent growth of [KEAP1-mutant cancer cells].
In vitro	BPK-29 substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].

Chemical Properties

Molecular Weight	506.46
Formula	C26H33Cl2N3O3
Cas No.	2444815-73-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 62.5 mg/mL (123.41 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9745 mL	9.8724 mL	19.7449 mL	98.7245 mL
5 mM	0.3949 mL	1.9745 mL	3.9490 mL	19.7449 mL
10 mM	0.1974 mL	0.9872 mL	1.9745 mL	9.8724 mL
20 mM	0.0987 mL	0.4936 mL	0.9872 mL	4.9362 mL
50 mM	0.0395 mL	0.1974 mL	0.3949 mL	1.9745 mL
100 mM	0.0197 mL	0.0987 mL	0.1974 mL	0.9872 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

inhibitBPK 29 HydrochlorideBPK 29BPK29BPK-29InhibitorBPK-29 HydrochlorideBPK 29 hydrochlorideBPK29 hydrochlorideBPK29 Hydrochloride