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BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 185 € | In Stock | |
5 mg | 424 € | In Stock | |
10 mg | 626 € | In Stock | |
25 mg | 937 € | In Stock | |
50 mg | 1.311 € | In Stock | |
1 mL x 10 mM (in DMSO) | 509 € | In Stock |
Description | BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it. |
In vitro | Treatment of HepG2 cells with BRD0418 for 6 hours resulted on average in 3.5-fold up-regulation of TRIB1 transcript levels, with half-maximal effect achieved at 2.3 μM concentration of the compound[1]. |
Alias | BRD-0418, BRD 0418 |
Molecular Weight | 488.57 |
Formula | C29H32N2O5 |
Cas No. | 1565827-99-7 |
Smiles | C(O)[C@H]1[C@]2([C@](C=3C(O2)=CC=C(N(C)C)C3)(C[C@@H](CC(NCC4=CC=C(OC5=CC=CC=C5)C=C4)=O)O1)[H])[H] |
Relative Density. | 1.220 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (112.57 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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