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BRD4 Inhibitor-28

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Catalog No. T78851Cas No. 2468960-80-5

BRD4 Inhibitor-28 (Compound 18), an orally active molecule, selectively inhibits the bromodomains of BRD4 (BRD4-BD1 and BRD4-BD2) with IC50 values of 15 and 55 nM, respectively. It also demonstrates inhibition of BRD2-BD1, BRD3-BD1, and BRDT-BD1 with IC50 values of 19, 25, and 68 nM, respectively. Furthermore, this compound exhibits anti-melanoma activity [1].

BRD4 Inhibitor-28

BRD4 Inhibitor-28

😃Good
Catalog No. T78851Cas No. 2468960-80-5
BRD4 Inhibitor-28 (Compound 18), an orally active molecule, selectively inhibits the bromodomains of BRD4 (BRD4-BD1 and BRD4-BD2) with IC50 values of 15 and 55 nM, respectively. It also demonstrates inhibition of BRD2-BD1, BRD3-BD1, and BRDT-BD1 with IC50 values of 19, 25, and 68 nM, respectively. Furthermore, this compound exhibits anti-melanoma activity [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,6708-10 weeks
50 mg$2,1808-10 weeks
100 mg$2,8008-10 weeks
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Product Introduction

Bioactivity
Description
BRD4 Inhibitor-28 (Compound 18), an orally active molecule, selectively inhibits the bromodomains of BRD4 (BRD4-BD1 and BRD4-BD2) with IC50 values of 15 and 55 nM, respectively. It also demonstrates inhibition of BRD2-BD1, BRD3-BD1, and BRDT-BD1 with IC50 values of 19, 25, and 68 nM, respectively. Furthermore, this compound exhibits anti-melanoma activity [1].
Chemical Properties
Molecular Weight387.43
FormulaC23H21N3O3
Cas No.2468960-80-5
Storage & Solubility Information
StorageShipping with blue ice.

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