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CD73-IN-18
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Catalog No. T200672Cas No. 3037968-61-6
CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.
CD73-IN-18
😃Good
Catalog No. T200672Cas No. 3037968-61-6
CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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MethADP (Adenosine 5'-(α,β-methylene)diphosphate) is a specific CD73 inhibitor that inhibits the enzyme ecto-5′-nucleotidase (ecto), which has been used in the study of neurological and cardiovascular diseases.
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Oleclumab (MEDI9447) is a human anti-CD73 monoclonal antibody with anticancer activity that inhibits the extracellular enzyme CD73 nucleic acid exonuclease activity, inhibits the adenosine pathway, and can be used for the study of metastatic desmoplasia-resistant prostate cancer.
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CD73-IN-1
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CD73-IN-1 is a CD73 inhibitor with anticancer activity.
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Mupadolimab
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Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.
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CD73-IN-16
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CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.
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CD73-IN-17
T200431
CD73-IN-17 (compound 19) is an inhibitor of CD73 with an IC50 of 0.1 μM against hCD73. It is applicable in cancer research.
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Dresbuxelimab
AK-119
T806032550560-20-6
Dresbuxelimab (AK-119), an IgG-κ monoclonal antibody, selectively targets CD73 and is commonly produced using a Chinese Hamster Ovary (CHO) cell expression system [1].
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Product Introduction
Bioactivity
Chemical Properties
| Description | CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research. |
| Molecular Weight | 375.38 |
| Formula | C20H17N5O3 |
| Cas No. | 3037968-61-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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