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Ceftaroline fosamil inner salt

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Catalog No. T39816Cas No. 229016-73-3
Alias TAK-599 free acid, PPI0903freeacid

Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection.

Ceftaroline fosamil inner salt

Ceftaroline fosamil inner salt

😃Good
Catalog No. T39816Alias TAK-599 free acid, PPI0903freeacidCas No. 229016-73-3
Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection.
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Product Introduction

Bioactivity
Description
Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection.
In vivo
Ceftaroline fosamil inner salt (s.c.) is effective in mitigating systemic infections induced by S. aureus N133 in mice, with ED50 values between 1.60 and 2.37 mg/kg[1]. At a 10 mg/kg (s.c.) dose, it is rapidly metabolized in the bloodstream of rats and monkeys, converting efficiently into T-91825[1].
AliasTAK-599 free acid, PPI0903freeacid
Chemical Properties
Molecular Weight684.67
FormulaC22H21N8O8PS4
Cas No.229016-73-3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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