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Ceftaroline fosamil

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Catalog No. T7387Cas No. 400827-46-5
Alias TAK-599, PPI0903

Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.

Ceftaroline fosamil

Ceftaroline fosamil

🥰Excellent
Catalog No. T7387Alias TAK-599, PPI0903Cas No. 400827-46-5
Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.
Pack SizePriceAvailabilityQuantity
1 mg$54In Stock
5 mg$128In Stock
10 mg$213In Stock
25 mg$397In Stock
50 mg$622In Stock
100 mg$885In Stock
1 mL x 10 mM (in DMSO)$215In Stock
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Related Compound Libraries of "Ceftaroline fosamil"

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Purity:≥98%
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Product Introduction

Bioactivity
Description
Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.
In vivo
Ceftaroline fosamil 600 mg given every 12 h was superior to ceftriaxone 2 g given every 24 h for the treatment of Asian patients with PORT III-IV community-acquired pneumonia. These data suggest that ceftaroline fosamil should be regarded as an alternative to ceftriaxone in empirical treatment regimens for this patient population.
AliasTAK-599, PPI0903
Chemical Properties
Molecular Weight744.74
FormulaC24H25N8O10PS4
Cas No.400827-46-5
SmilesCCON=C(C1=NSC(=N1)NP(=O)(O)O)C(=O)NC2C3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)O.CC(=O)[O-]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 14 mg/mL (32.22 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3428 mL6.7138 mL13.4275 mL67.1375 mL
5 mM0.2686 mL1.3428 mL2.6855 mL13.4275 mL
10 mM0.1343 mL0.6714 mL1.3428 mL6.7138 mL
20 mM0.0671 mL0.3357 mL0.6714 mL3.3569 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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