Shopping Cart

Remove All

Your shopping cart is currently empty

CHK1 inhibitor

Catalog No. T10793Cas No. 2097938-64-0

CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
25 mg	$2,270	10-14 weeks
50 mg	$2,980	10-14 weeks
100 mg	$4,000	10-14 weeks

Bulk & Custom

Add to Cart

Questions

Product Introduction

Bioactivity

Description	CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.
Alias	GDC-0575 analog

Chemical Properties

Molecular Weight	377.28
Formula	C17H21BrN4O
Cas No.	2097938-64-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 150 mg/mL (397.58 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6506 mL	13.2528 mL	26.5055 mL	132.5276 mL
5 mM	0.5301 mL	2.6506 mL	5.3011 mL	26.5055 mL
10 mM	0.2651 mL	1.3253 mL	2.6506 mL	13.2528 mL
20 mM	0.1325 mL	0.6626 mL	1.3253 mL	6.6264 mL
50 mM	0.0530 mL	0.2651 mL	0.5301 mL	2.6506 mL
100 mM	0.0265 mL	0.1325 mL	0.2651 mL	1.3253 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc