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Cholic acid sodium hydrate
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Catalog No. T75427Cas No. 206986-87-0
Cholic acid sodium hydrate is a natural and orally active bile acid that is synthesized primarily by the liver and secreted into the bile, where it plays an important role in the digestive process, aiding in the absorption of fats by emulsifying them, as well as participating in the excretion of cholesterol and regulating the metabolism of bile acids.
Cholic acid sodium hydrate
😃Good
Catalog No. T75427Cas No. 206986-87-0
Cholic acid sodium hydrate is a natural and orally active bile acid that is synthesized primarily by the liver and secreted into the bile, where it plays an important role in the digestive process, aiding in the absorption of fats by emulsifying them, as well as participating in the excretion of cholesterol and regulating the metabolism of bile acids.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $34 | Backorder | |
| 100 mg | $52 | Backorder | |
| 500 mg | $115 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Cholic acid sodium hydrate is a natural and orally active bile acid that is synthesized primarily by the liver and secreted into the bile, where it plays an important role in the digestive process, aiding in the absorption of fats by emulsifying them, as well as participating in the excretion of cholesterol and regulating the metabolism of bile acids. |
| In vitro | Cholic acid sodium hydrate (1 mg/mL, 30 minutes) competitively binds to Na+/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells.[1] |
| In vivo | Cholic acid sodium hydrate (1% cholic acid supplemented diet, oral, 14 days) may reduce SHP (small heterodimer partner) protein expression via upregulation of miR142-3p. [2] |
| Molecular Weight | 448.57 |
| Formula | C24H41NaO6 |
| Cas No. | 206986-87-0 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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