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COX/5-LO-IN-1
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Catalog No. T13263Cas No. 154355-75-6
Alias Atreleuton analog
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
COX/5-LO-IN-1
😃Good
Catalog No. T13263Alias Atreleuton analogCas No. 154355-75-6
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states. |
| Targets&IC50 | COX:, 5-LOX:2 μM |
| In vitro | COX / 5-LO-IN-1 reduces the biosynthesis of leukotrienes B4, C4, D4 and E4 and cyclooxygenase products (such as prostaglandins and thromboxanes) and can be used to treat inflammation and allergic diseases[1]. COX/5-LO-IN-1 shows inhibitory activities against 5-lipoxygenase(IC50 of 0.2 μM in human whole blood)[2]. |
| Alias | Atreleuton analog |
| Molecular Weight | 318.37 |
| Formula | C16H15FN2O2S |
| Cas No. | 154355-75-6 |
| Relative Density. | 1.37 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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