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D75-4590
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D75-4590
Catalog No. T61194Cas No. 384376-42-5
D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $217 | In Stock | |
| 50 mg | $346 | In Stock | |
| 100 mg | $499 | In Stock | |
| 500 mg | $987 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $69 | In Stock |
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase. |
| In vitro | D75-4590 demonstrates efficacy against various Candida species, even those resistant to fluconazole. Notably, most strains of C. albicans, C. tropicalis, and C. parapsilosis exhibit trailing growth patterns akin to those seen with azole treatments [1]. |
| Molecular Weight | 349.47 |
| Formula | C21H27N5 |
| Cas No. | 384376-42-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (14.31 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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