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diABZI-C2-NH2
🥰Excellent
Catalog No. T39597Cas No. 2137975-93-8
diABZI-C2-NH2 is an agonist of the interferon gene STING that modulates STING-dependent type I interferon production and can be used to study STING-mediated diseases.
diABZI-C2-NH2
🥰Excellent
Purity: 96.09%
Catalog No. T39597Cas No. 2137975-93-8
diABZI-C2-NH2 is an agonist of the interferon gene STING that modulates STING-dependent type I interferon production and can be used to study STING-mediated diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $699 | In Stock |
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T55162138299-34-8In house
diABZI STING agonist-1 (trihydrochloride) is a stimulator of interferon genes (STING) receptor agonist.
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CitedSelect Batch
Purity:96.09%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | diABZI-C2-NH2 is an agonist of the interferon gene STING that modulates STING-dependent type I interferon production and can be used to study STING-mediated diseases. |
| In vitro | diABZIs can enhance binding to STING and cellular function. Intravenous administration of diABZI STING agonists to immunocompetent syngeneic colon tumor-bearing mice induces strong antitumor activity, leading to complete and durable tumor regression. The conjugated diABZI-C2-NH2 can be covalently immobilized onto agarose beads for affinity capture of potential target proteins from THP1 cell lysates[1]. |
| Molecular Weight | 721.81 |
| Formula | C36H43N13O4 |
| Cas No. | 2137975-93-8 |
| Smiles | CCn1nc(C)cc1C(=O)Nc1nc2cc(ccc2n1CCCCn1c(NC(=O)c2cc(C)nn2CC)nc2cc(ccc12)C(=O)NCCN)C(N)=O |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (110.83 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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