DL-Metanephrine-d3 Hydrochloride is L-Metanephrine labeled with deuterium atoms and can be used to study the metabolic flow of L-Metanephrine in the body.

In some cases, deuterated compounds may offer advantages over nondeuterated compounds, often through altered clearance. Deuteration may also redirect metabolic pathways in a direction that reduces toxicity. Approval of other deuterated compounds may soon follow. Clinicians need to become familiar with the dosing, efficacy, potential side effects, and unique metabolic profiles of these new entities.[2]