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DYRKs-IN-1 has antitumor activity. DYRKs-IN-1 is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,420 | 3-6 months | |
50 mg | $3,180 | 3-6 months | |
100 mg | $4,300 | 3-6 months |
Description | DYRKs-IN-1 has antitumor activity. DYRKs-IN-1 is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively. |
Targets&IC50 | DYRK1A:5 nM , DYRK1B:9 nM |
In vitro | Dyrks-in-1 enhanced the efficacy of human colon cancer cell line SW 620 with EC50 at 27 nM. |
Molecular Weight | 588.06 |
Formula | C30H30ClN7O4 |
Cas No. | 1387090-01-8 |
Relative Density. | 1.53 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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