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PDE4-IN-20

🥰Excellent
Catalog No. T50023Cas No. 223500-15-0

ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate, also known as EAPT, is a potent and selective PDE4 inhibitor that regulates intracellular cyclic adenosine monophosphate (cAMP) levels. It has been used in a variety of scientific applications, including the study of cAMP-mediated signaling pathways, and has potential as a therapeutic agent for the treatment of inflammatory and immune-related diseases.

PDE4-IN-20

PDE4-IN-20

🥰Excellent
Purity: 98.84%
Catalog No. T50023Cas No. 223500-15-0
ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate, also known as EAPT, is a potent and selective PDE4 inhibitor that regulates intracellular cyclic adenosine monophosphate (cAMP) levels. It has been used in a variety of scientific applications, including the study of cAMP-mediated signaling pathways, and has potential as a therapeutic agent for the treatment of inflammatory and immune-related diseases.
Pack SizePriceAvailabilityQuantity
5 mg$32In Stock
10 mg$47In Stock
25 mg$82In Stock
50 mg$119In Stock
100 mg$179In Stock
200 mg$273In Stock
1 mL x 10 mM (in DMSO)$40In Stock
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Purity:98.84%
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Product Introduction

Bioactivity
Description
ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate, also known as EAPT, is a potent and selective PDE4 inhibitor that regulates intracellular cyclic adenosine monophosphate (cAMP) levels. It has been used in a variety of scientific applications, including the study of cAMP-mediated signaling pathways, and has potential as a therapeutic agent for the treatment of inflammatory and immune-related diseases.
Chemical Properties
Molecular Weight299.25
FormulaC13H12F3N3O2
Cas No.223500-15-0
SmilesC(F)(F)(F)C=1N(N=CC1C(OCC)=O)C2=CC=C(N)C=C2
Relative Density.1.39 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (150.37 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3417 mL16.7084 mL33.4169 mL167.0844 mL
5 mM0.6683 mL3.3417 mL6.6834 mL33.4169 mL
10 mM0.3342 mL1.6708 mL3.3417 mL16.7084 mL
20 mM0.1671 mL0.8354 mL1.6708 mL8.3542 mL
50 mM0.0668 mL0.3342 mL0.6683 mL3.3417 mL
100 mM0.0334 mL0.1671 mL0.3342 mL1.6708 mL

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Keywords

ethyl 1(4aminophenyl)5(trifluoromethyl)1Hpyrazole4carboxylateethyl 1 (4 aminophenyl) 5 (trifluoromethyl) 1H pyrazole 4 carboxylate
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