Shopping Cart

Remove All
Your shopping cart is currently empty

Fmoc-PEG1-CH2CH2-NHS ester

Name: Fmoc-PEG1-CH2CH2-NHS ester
Brand: TargetMol
SKU: T15327
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T15327Cas No. 1807521-05-6

Fmoc-PEG1-CH2CH2-NHS ester is a polyethylene glycol (PEG)-derived linker engineered for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Fmoc-PEG1-CH2CH2-NHS ester

🥰Excellent

Catalog No. T15327Cas No. 1807521-05-6

Fmoc-PEG1-CH2CH2-NHS ester is a polyethylene glycol (PEG)-derived linker engineered for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Product information is being updated, if you want to purchase, please click the bulk custom button.

Bulk & Custom

Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Fmoc-PEG1-CH2CH2-NHS ester is a polyethylene glycol (PEG)-derived linker engineered for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].
In vitro	PROTACs, comprising two ligands connected by a linker—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Chemical Properties

Molecular Weight	452.46
Formula	C₂₄H₂₄N₂O₇
Cas No.	1807521-05-6
Relative Density.	1.38 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PEGsFmoc-PEG1-CH2CH2-NHS esterFmoc-PEG-1-CH2CH2-NHS esterFmocPEG1CH2CH2NHS esterFmoc PEG1 CH2CH2 NHS esterAlkyl/ether