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FR104
🥰Excellent
Catalog No. T77481
Alias FR 104
FR104 is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG.
FR104
FR104
🥰Excellent
Catalog No. T77481Alias FR 104
FR104 is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $197 | In Stock | |
| 5 mg | $596 | In Stock | |
| 10 mg | $959 | In Stock | |
| 25 mg | $1,420 | In Stock | |
| 50 mg | $1,920 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | FR104 is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG. |
| Targets&IC50 | T lymphocyte:0.10 μg/mL |
| In vitro | FR104 inhibited T lymphocyte proliferation in a dose-dependent manner in mixed lymphocyte response assay with IC50 = 0.10 μg/mL. |
| In vivo | In juvenile baboons, FR104 is given intravenously at 5 mg/kg and the half-life of elimination is 8.4 days. |
| Alias | FR 104 |
| Molecular Weight | 145.5 kDa |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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