Shopping Cart
- Remove All
Your shopping cart is currently empty
G-5555 hydrochloride (1648863-90-4 free base)
😃Good
Catalog No. T11342
Alias G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
G-5555 hydrochloride (1648863-90-4 free base)
😃Good
Catalog No. T11342Alias G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $144 | Backorder | |
| 10 mg | $232 | Backorder | |
| 25 mg | $495 | Backorder | |
| 50 mg | Inquiry | Backorder | |
| 100 mg | Inquiry | Backorder | |
| 1 mL x 10 mM (in DMSO) | $167 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "G-5555 hydrochloride (1648863-90-4 free base)"
5-Aminosalicylic Acid
Cited
Mesalazine, Mesalamine, 5-ASA
T064689-57-6
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
- $45
Size
QTY
CitedFingolimod hydrochloride
FTY720 HCl, Fingolimod (FTY720) HCl
T2539162359-56-0
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
- $35
Size
QTY
Fingolimod Cited
FTY-720A, FTY-720
T7939162359-55-9
Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
- $50
Size
QTY
CitedPF-3758309 hydrochloride
PF-03758309 hydrochloride
T42301279034-84-2
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
- $37
Size
QTY
FRAX597
T60141286739-19-2
FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).
- $34
Size
QTY
ZINC194100678
T602691995025-05-2
ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM. ZINC194100678 showed strong anti-proliferation activity, with IC50 value of 40.16μM against MDA-MB-231.
- $117
Size
QTY
FRAX486 HCL(1232030-35-1 free base)
T6840L
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
- $30
Size
QTY
PIR 3.5
6,6′-Dithiodi(2-naphthol)
T231606088-51-3
PIR 3.5 (6,6′-Dithiodi(2-naphthol)) is a negative control of IPA 3 which is a Pak1 inhibitor.
- $37
Size
QTY
GNE 2861
T164291394121-05-1
GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.
- $36
Size
QTY
NVS-PAK1-1
T163671783816-74-9
NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).
- $44
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM. |
| Targets&IC50 | PAK2:11 nM (ki), PAK1:3.7 nM (ki) |
| Alias | G-5555 hydrochloride |
| Molecular Weight | 529.42 |
| Formula | C25H26Cl2N6O3 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (188.89 mM), Sonication is recommended. H2O: 16.67 mg/mL (31.49 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
| |||||||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy G-5555 hydrochloride (1648863-90-4 free base) | purchase G-5555 hydrochloride (1648863-90-4 free base) | G-5555 hydrochloride (1648863-90-4 free base) cost | order G-5555 hydrochloride (1648863-90-4 free base) | G-5555 hydrochloride (1648863-90-4 free base) chemical structure | G-5555 hydrochloride (1648863-90-4 free base) formula | G-5555 hydrochloride (1648863-90-4 free base) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.