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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $37 | In Stock | |
2 mg | $50 | In Stock | |
5 mg | $74 | In Stock | |
10 mg | $120 | In Stock | |
25 mg | $191 | In Stock | |
50 mg | $352 | In Stock | |
100 mg | $553 | In Stock | |
1 mL x 10 mM (in DMSO) | $116 | In Stock |
Description | PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival. |
Alias | PF-03758309 hydrochloride |
Molecular Weight | 527.08 |
Formula | C25H31ClN8OS |
Cas No. | 1279034-84-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (85.37 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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